Please join the next MS Xchange Network Conference Series on December 05, at 5pm (EST) for a talk by Dr. Veronique Miron.
Dr. Miron will present on Microglia as key regulators of de- and remyelination in MS.
If you'd like to attend, you should register in advance.
Microglia as key regulators of de- and remyelination in MS
Chronic demyelination due to failed remyelination underpin progressive clinical deterioration in MS. The lack of therapies preventing MS progression highlight the need to elucidate the underpinning mechanisms. Our lab discovered that microglia have critical protective and regenerative roles in preventing spontaneous focal demyelination and promoting remyelination. Here, I will show our latest work revealing ways in which microglia regulate oligodendrocyte health and infiltrating T cell responses with relevance to MS, and a surprising new model of progressive MS pathology. This has important implications in devising novel therapeutic strategies to support myelin health in MS.
Speaker: Dr. Veronique Miron
Chair: Dr. Jack Antel
Veronique Miron, PhD, is the recently appointed John David Eaton Chair of Multiple Sclerosis Research at the BARLO MS Centre, Keenan Research Centre for Biomedical Science in Toronto, Canada, and Full Professor at the Department of Immunology at The University of Toronto. She has investigated remyelination in MS for 20 years, completing her PhD at the Montreal Neurological Institute, postdoctoral fellowship at the Scottish Centre for Regenerative Medicine, then setting up her independent lab at The University of Edinburgh. Her team's research focus is to harness the beneficial glial and immune interactions that regulate myelin health with the aim of developing novel protective and regenerative therapeutic strategies for disorders like MS.